DERMATOLOGIST-LED SKIN LONGEVITY EDUCATION.

The science & strategy of skin longevity.

Understand how skin functions, adapts, ages, and recovers and learn evidence-based strategies designed to support healthier, more resilient skin over time.

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Learn the framework

WHAT IS SKINSPAN™?

Skin aging is more than time.

SKINSPAN™ is the duration of life during which skin maintains its highest level of performance including healthy structure and function, resilience, regenerative capacity, and aesthetic quality. It translates dermatology, stress biology, lifestyle science, and regenerative medicine into practical strategies for extending that period of skin health.

Discover our perspective

PROTECT

01

Reduce preventable damage from ultraviolet radiation, environmental exposures, lifestyle factors, and other sources of cumulative skin stress.

REGULATE

02

Support barrier integrity, inflammatory control, neurohormonal signaling, hydration, and recovery from daily stressors.

REVITALIZE

03

Use evidence-based skincare, procedures, regenerative strategies, and healthy behaviors to support repair, renewal, structure, and function.

Explore the SKINSPAN™ framework

THE EXPOSOME

Your skin remembers more than birthdays.

Ultraviolet radiation, pollution, smoking, nutrition, sleep, hormonal changes, psychological stress, inflammation, and other exposures can influence the way skin ages and recovers. Understanding these factors creates an opportunity to think proactively about skin healthspan.

LEARN THE SCIENCE

Ideas for a longer skin healthspan.

An infographic titled 'What Is Skin Longevity?' showing a woman's face and a cross-section of skin layers with labels for epidermis, dermis, and collagen & elastin. Icons represent skin damage prevention, resilient adaptation, and vitality restoration. The infographic emphasizes skin health for resilience and healthy aging over time.

What Is Skin Longevity? Understanding Your SKINSPAN™

Skin longevity is not about stopping time. It is about preserving the years your skin can function, protect, recover, and perform at its best.

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An infographic titled 'The Stressed Skin Exposome' illustrating how psychological stress and external environmental factors influence skin health. It shows the brain stress response, including cortisol, neurotransmitters, and immune factors, leading to skin responses such as inflammation, barrier dysfunction, collagen breakdown, and vascular changes. The infographic also depicts visible skin impacts like increased sensitivity, flare-ups, accelerated aging, pigmentary changes, barrier dysfunction, enlarged pores, dullness, and vascular changes.

Stress Is a Skin Aging Factor: Understanding the Stressed Skin Exposome

Psychological stress is not ‘just in your head.’ Skin participates in a two-way conversation with the nervous, endocrine, and immune systems.

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A graphic illustrating four domains that shape long-term skin performance, including skincare, lifestyle, dermatologic strategy, and regenerative aesthetics, with symbols and images of skincare products, healthy lifestyle habits, medical device treatment, and skin tissue.

The SKINSPAN™ Framework: Protect • Regulate • Revitalize

Skin longevity is not built by doing more. It is built by doing the right things in the right sequence, for the right person, over time.

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WATCH SKINSPAN™

The science, made clear.

Short, physician-led education translating complex dermatology and longevity science into practical insights.

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A woman in a white lab coat with curly hair and blue eyes, smiling and posing with her hand near her face, in a medical or clinical setting.

THE FOUNDER

Created by Dr. Marianna Blyumin Karasik.

Dr. Marianna Blyumin Karasik is a board-certified dermatologist, educator, researcher, and entrepreneur with a special interest in skin longevity, stress biology, skin resilience, regenerative dermatology, and healthy aging. As the creator of SKINSPAN™, she translates emerging dermatology science into practical strategies to optimize skin function, recovery, and resiliency over time.

She is also the co-founder of Precision Skin & Body Institute and the founder of Stamina® Cosmetics, bringing together clinical dermatology, aesthetics, research, and wellness in her approach to lifelong skin health.

About SKINSPAN™

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The science of skin longevity is evolving.

Receive evidence-based insights on skin resilience, stress, healthy aging, skincare, and regenerative dermatology.